French workers have already carried out six common strikes since the beginning of September over proposed pension reforms that would increase the minimum retirement age to 62.
Half of flights to Paris Orly airport, and around a third of services to other French airports, face cancellation, according to the country’s aviation right.
Short-haul flights will be hit hardest, with the vast majority of long-haul flights expected to operate as normal.
British Airways, EasyJet and Air France said the strikes are certain to cause delays and some cancellations. All three airlines urged passengers to check the status of their flights before travelling to the airport. Ryanair has already published on its site a list of more than 200 cancelled flights to destinations across Europe.
Train services are also likely to be affected. During previous walkouts, around two thirds of France's high-speed TGV and usual regional services were cancelled, and Paris metro services were also affected.